Here’s the description for episode 16.
Safe House (9:00-10:00 p.m. ET)
JIM BEAVER RETURNS A dangerous creature is accidentally released into an old house, attacking a mother and her child, leaving them both in a coma. Sam (Jared Padalecki) and Dean (Jensen Ackles) learn that Bobby (guest star Jim Beaver) and Rufus (guest star Steven Williams) once tracked the same entity so the Winchesters look to the past to come up with a plan to catch the monster before any one dies. Stefan Pleszczynski directed the episode written by Robbie Thompson. (#1116) Original airdate 3/23/16.
Examiner.com has a more detailed article on the episode and rest of the season.
The return of Bobby and Rufus! I’m looking forward to this. I love both Rufus and Bobby. What kind of entity do you think they are fighting? How will Sam and Dean figure out that Bobby and Rufus fought it? Are there notes still at the cabin? All of Bobby’s things were destroyed when the Leviathans destroyed his house in season seven. Are you looking forward to this? Tell us in the comments or in the discussion thread for episode 16.