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After the success of the Seattle Marathon, Jared and Genevieve Padalecki have decided to take on The Boston Marathon for charity.
Here's the official announcement.
More below cut.
Jared teased the event on Twitter
 The Crowdrise campaign has more information. From Genevieve

Hi Everybody!

It is with incredible excitement, and great humility, to let you know you that my husband and I will be running the Boston Marathon on April 15th, 2019!  

We will be endeavoring on this journey to help raise awareness and funds for a cause that we believe in wholeheartedly.  Dream Big! Is a 501c(3) supporting, outfitting, supplying, encouraging and providing opportunities for young girls who, due to economic circumstances, are unable to participate.  This incredible organization has provided over $200,000 worth of sports equipment, uniforms, and footwear in such sports as track and field, volleyball, soccer, double dutch, etc.  The scholarship programs at DreamBig! have allowed young female athletes to attend “basketball college showcases, soccer and volleyball camps, dance classes, and gymnastics lessons, and hundreds of girls attended Dream Big! Sports Clinics in partnership with local college sports teams.” DreamBig! helps move mountains for young girls and this speaks to mine and my husband’s hearts.  

Both Genevieve and Jared have signed the Crowdriser post.
Jared added.

t’s unfortunate, but also no secret, that male sports receive more attention and support from the general public. The athletes are paid more. The events are televised more regularly and on more channels, etc... I would love to take some part in raising awareness and increasing availability for girls, young and old, to learn some of the invaluable things that I was fortunate to learn growing up. 

Over the next few weeks, we will be sharing our story with you as we train for The Boston Marathon - one of the most grueling and demanding courses in the US. It’s going to be hard. It’s going to hurt. But it’s going to be worth it.

We are so lucky to have such generous stars in our Supernatural family.
Jared and Gen have not yet  made an official announcement about the event. We will update this story as more information becomes available.